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Autor: Hanne Hjorth Tonnesen
ISBN-13: 9780415303231
Einband: Buch
Seiten: 452
Gewicht: 748 g
Format: 239x165x28 mm
Sprache: Englisch
Erscheinungsdatum: 01.06.2004

Photostability of Drugs and Drug Formulations, 2nd Edition

Introduction: Photostability Testing of Drugs and Drug Formulations - Why and How? H. Hjorth Tonnesen Photophysical and Photochemical Aspects of Drug Stability, D.E. Moore Standardization of Kinetic Studies of Photodegradation Reactions, D.E. Moore Rationalizing the Photochemistry of Drugs, A. Albini and E. Fasani Technical Requirements and Equipment for Photostability Testing, J. Boxhammer and A. Schonlein Photostability Testing: Design and Interpretation of Tests on New Drug Substances and Dosage Forms, N.H. Anderson and S.J. Byard The Questions Most Frequently Asked, H. Hjorth Tonnesen and S.W. Baertschi Inconsistencies and Deficiencies Which Exist in the Current Official Regulations Concerning the Photolytic Degradation of Drugs, J.C. Hung Benefits and Adverse Effects from the Combination of Drugs and Light, J. Moan and P. Juzenas In Vitro Screening of the Photoreactivity of Antimalarials. A Test Case, H.Hjorth Tonnesen and S. Kristensen Screening of Dyes, Drugs and Dietary Supplements for Ocular Phototoxicity, J.E. Roberts Photochemical and Photophysical Methods Used in the Study of Drug Photoreactivity, S. Navaratnam Addressing the Problem of Light Instability During Formulation Development, D.R. Merrifield, P.L. Carter, D. Clapham, and F.D. Sanderson Photostability of Parenteral Products, S. Kristensen Photoactivated Drugs and Drug Formulations, J. Karlsen and H . Hjorth Tonnesen Formulation Approaches for Improving Solubility and its Impact on Drug Photostability, H.Hjorth Tonnesen Appendix 1: Useful Terms and Expressions in the Photoreactivity Testing of Drugs Appendix 2: Relevant Literature on the Photostability of Specific Drug Substances and Drug Formulations
Covering in vitro and in vivo aspects of drug photoreactivity, this book provides the background necessary for the planning of standardized photochemical stability studies as a part of drug development and formulation work. The second edition of a bestseller, it focuses on standardization of photostability testing of drug substances and products, in vitro photoreactivity screening of drugs, and various aspects of the formulation of photoreactive substances. With chapter authors drawn from an international panel of experts, the second edition has been completely revised and updated to emphasize the significance of information and knowledge on drug photoreactivity in a pharmaceutical context.

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Autor: Hanne Hjorth Tonnesen
ISBN-13:: 9780415303231
ISBN: 0415303230
Erscheinungsjahr: 01.06.2004
Gewicht: 748g
Seiten: 452
Sprache: Englisch
Auflage 00002, Revised
Sonstiges: Buch, 239x165x28 mm